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Karen MacDonald Selected Research

Filgrastim (Neupogen)

1/2020Febrile neutropenia hospitalization due to pegfilgrastim on-body injector failure compared to single-injection pegfilgrastim and daily injections with reference and biosimilar filgrastim: US cost simulation for lung cancer and non-Hodgkin lymphoma.
6/2019Outcomes of chemotherapy-induced (febrile) neutropenia prophylaxis with biosimilar filgrastim (Zarzio®) initiated "same-day" (< 24 h), "per-guidelines" (24-72 h), and "late" (> 72 h): findings from the MONITOR-GCSF study.
3/2019Chemotherapy-induced neutropenia/febrile neutropenia prophylaxis with biosimilar filgrastim in solid tumors versus hematological malignancies: MONITOR-GCSF study.
1/2018Reply: Cost-efficiency analyses for the US of biosimilar filgrastim-sndz, reference filgrastim, pegfilgrastim, and pegfilgrastim with on-body injector in the prophylaxis of chemotherapy-induced (febrile) neutropenia.
10/2017Cost-efficiency analyses for the US of biosimilar filgrastim-sndz, reference filgrastim, pegfilgrastim, and pegfilgrastim with on-body injector in the prophylaxis of chemotherapy-induced (febrile) neutropenia.
10/2017Expanded access to cancer treatments from conversion to neutropenia prophylaxis with biosimilar filgrastim-sndz.
1/2017Over- and under-prophylaxis for chemotherapy-induced (febrile) neutropenia relative to evidence-based guidelines is associated with differences in outcomes: findings from the MONITOR-GCSF study.
1/2017Chemotherapy-induced (febrile) neutropenia prophylaxis with biosimilar filgrastim in elderly versus non-elderly cancer patients: Patterns, outcomes, and determinants (MONITOR-GCSF study).
2/2016Treatment patterns and outcomes in the prophylaxis of chemotherapy-induced (febrile) neutropenia with biosimilar filgrastim (the MONITOR-GCSF study).
1/2016Erratum to: Treatment patterns and outcomes in the prophylaxis of chemotherapy-induced (febrile) neutropenia with biosimilar filgrastim (the MONITOR-GCSF study).
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Karen MacDonald Research Topics

Disease

17Neoplasms (Cancer)
01/2021 - 01/2008
12Chemotherapy-Induced Febrile Neutropenia
01/2021 - 03/2011
7Febrile Neutropenia
11/2021 - 03/2011
6Anemia
11/2021 - 01/2008
5Neutropenia
11/2021 - 01/2017
5Hypertension (High Blood Pressure)
01/2021 - 05/2009
3Myelodysplastic Syndromes (Myelodysplastic Syndrome)
01/2017 - 06/2011
2Breast Neoplasms (Breast Cancer)
01/2022 - 01/2021
2BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
12/2021 - 05/2009
2Asthma (Bronchial Asthma)
01/2021 - 09/2017
2Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2021 - 01/2020
2Cardiovascular Diseases (Cardiovascular Disease)
01/2021 - 06/2011
2Macular Degeneration (Age-Related Maculopathy)
01/2020 - 01/2017
2Type 2 Diabetes Mellitus (MODY)
06/2019 - 12/2016
2Urticaria (Hives)
01/2019 - 01/2018
1Gallstones (Gallstone)
01/2022
1COVID-19
01/2022
1Wound Infection (Wound Infections)
01/2022
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
11/2021
1Thrombocytopenia (Thrombopenia)
11/2021
1Pancreatic Neoplasms (Pancreatic Cancer)
11/2021
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2021
1Nausea
03/2020
1Vomiting
03/2020
1Lung Neoplasms (Lung Cancer)
01/2020
1Macular Edema
01/2020
1Hematologic Neoplasms (Hematological Malignancy)
03/2019
1Chronic Urticaria
01/2019
1Weight Gain
01/2019
1Pure Red-Cell Aplasia
01/2018
1Sarcoidosis (Schaumann Disease)
01/2017
1Chronic Disease (Chronic Diseases)
01/2017
1Coronary Artery Disease (Coronary Atherosclerosis)
01/2015
1Chronic Kidney Failure (Chronic Renal Failure)
11/2012
1Iron Overload
06/2011
1Multiple Myeloma
03/2011
1Ovarian Neoplasms (Ovarian Cancer)
03/2011
1Alzheimer Disease (Alzheimer's Disease)
10/2007

Drug/Important Bio-Agent (IBA)

22Biosimilar PharmaceuticalsIBA
01/2022 - 03/2011
13Filgrastim (Neupogen)FDA Link
01/2020 - 03/2011
9pegfilgrastim (Neulasta)FDA Link
01/2022 - 10/2017
4Valsartan (Vals)FDA Link
01/2021 - 05/2009
4Omalizumab (Xolair)FDA Link
01/2021 - 09/2017
3Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2022 - 01/2020
3Trastuzumab (Herceptin)FDA Link
01/2022 - 04/2015
3Doxorubicin (Adriamycin)FDA LinkGeneric
01/2022 - 01/2020
3Ranibizumab (Lucentis)FDA Link
01/2020 - 01/2017
3Granulocyte Colony-Stimulating Factor (G-CSF)IBA
10/2017 - 03/2011
3IronIBA
01/2017 - 06/2011
2Imatinib Mesylate (Gleevec)FDA Link
12/2021 - 05/2009
2Rituximab (Mabthera)FDA Link
01/2021 - 04/2015
2Antihypertensive Agents (Antihypertensives)IBA
01/2021 - 01/2017
2VildagliptinIBA
06/2019 - 12/2016
2Metformin (Glucophage)FDA LinkGeneric
06/2019 - 12/2016
2Epoetin Alfa (Epogen)FDA Link
01/2018 - 01/2014
2Antineoplastic Agents (Antineoplastics)IBA
04/2015 - 01/2014
2HematinicsIBA
04/2013 - 11/2012
2Proteins (Proteins, Gene)FDA Link
07/2010 - 01/2008
1Anti-Bacterial Agents (Antibiotics)IBA
01/2022
1SolutionsIBA
01/2022
1Carboplatin (JM8)FDA LinkGeneric
01/2022
1Docetaxel (Taxotere)FDA Link
01/2022
1trilaciclibIBA
11/2021
1folfirinoxIBA
11/2021
1Paclitaxel (Taxol)FDA LinkGeneric
01/2021
1Prednisone (Sone)FDA LinkGeneric
01/2021
1Hydrochlorothiazide (Esidrix)FDA LinkGeneric
01/2021
1pertuzumabIBA
01/2021
1Vincristine (Oncovin)FDA LinkGeneric
01/2021
1pembrolizumabIBA
08/2020
1Pharmaceutical PreparationsIBA
08/2020
1Neurokinin-1 Receptor AntagonistsIBA
03/2020
1Olanzapine (Zyprexa)FDA Link
03/2020
1Palonosetron (Aloxi)FDA Link
03/2020
1Dexamethasone (Maxidex)FDA LinkGeneric
03/2020
1Thalidomide (Thalomid)FDA Link
03/2020
1Etoposide (VP 16)FDA LinkGeneric
01/2020
1Colony-Stimulating Factors (Colony Stimulating Factor)IBA
06/2019
1Glycated Hemoglobin (Glycosylated Hemoglobin)IBA
06/2019
1Glucose (Dextrose)FDA LinkGeneric
06/2019
1AlbuminsIBA
01/2019
1Phosphates (Orthophosphate)IBA
01/2019
1Histamine Antagonists (Antihistamines)IBA
01/2019
1AntibodiesIBA
01/2018
1Adrenal Cortex Hormones (Corticosteroids)IBA
09/2017
1Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
01/2017
1Hemoglobins (Hemoglobin)IBA
04/2013
1Valsartan Drug Combination AmlodipineFDA Link
06/2011
1Rivastigmine (Exelon)FDA LinkGeneric
10/2007
1Cholinesterase Inhibitors (Anticholinesterases)IBA
10/2007

Therapy/Procedure

14Drug Therapy (Chemotherapy)
11/2021 - 01/2008
11Therapeutics
11/2021 - 10/2007
2Chelation Therapy (Therapy, Chelation)
05/2014 - 06/2011
1Laparoscopic Cholecystectomy
01/2022
1Injections
01/2020
1Renal Dialysis (Hemodialysis)
01/2018
1Antibiotic Prophylaxis
01/2017
1Cardiac Rehabilitation
01/2015
1Aftercare (After-Treatment)
07/2010